Introduction:
Hemorrhoids are abnormal anorectal vessel dilatations and distal displacements of normal anal cushions. Abnormal destructive changes are the hallmark of the disease. Supporting tissue inflammation and hyperplasia are commonly found in this condition. There are three major anal cushions and multiple minor cushions in anal canal. Various pathological changes in these cushions lead to the manifestation of the disease. These pathological changes include venous dilatation, vascular thrombosis, degenerative process in the collagen fibers and fibroelastic tissues, distortion and rupture of the anal subepithelial muscle. An inflammatory reaction in the vascular walls and surrounding supportive connective tissue is almost always accompanied by these pathological changes in the patients. This combine aetiology leads to mucosal ulcerations, ischemia, bleeding and thrombosis.Certain proteolytic enzymes e.g matrix metalloproteinase, which destroys the the extracellular supporting proteins specifically elastin, fibronectin, and collagen. This destructive activity leads to degenerative changes in capillary bed of anal canal which activates angioproliferative action by transforming growth factor β. This angioproleferative activity leads to neovascularization phenomenon which is commonly manifested in the hemorroid disease.
Classification of hemorrhoids:
On the basis of their location and degree of prolapse, hemorrhoids are classified into two distinct classes. Internal haemorrhoids and external haemorrhoids
1. Internal hemorrhoids:
Internal hemorrhoids originate from the inferior hemorrhoidal venous plexus above the dentate line and are covered by mucosa.
2. External hemorrhoids:
external hemorrhoids are dilated venules of this plexus located below the dentate line and are covered with squamous epithelium.
If the hemorrhoids arise from both, above and below the dentate line, it is know as mixed type or interno-external hemmorhoids.
Causes of Hemorrhoids:
Hemorrhoid is a multifactorial condition and manifests as a result of following aetiologies.
- Straining when you do something that's physically hard for example heavy weight lifting at gym can cause hemorrhoids.
- Excessive body weight as in obesity can cause straining while bowl movements and results in hemorrhoids.
- Pregnancy, when your growing uterus presses on your veins of lower abdomen including rectum and anal canal. This leads to engorged veins and pooling of blood which manifests as hemorrhoids.
- Continuous low fiber diet for large periods of time leads to diarrhoea and results in haemorrhoids
- Anal intercourse damages the normal anal mucosa, causes inflammation and disruption of the normal connective tissue which can ultimately lead to hemorrhoids.
- Chronic Constipation makes tool hard and difficult to pass leading to straining during bowl movements.
Clinical Manifestations:
Clinically hemorrhoids manifest as painless rectal bleeding associated with bowel movements and patients complaints about the blood dripping into toilet, incomplete evacuation and rectal fullness. Due to direct arteriovenous communication in hemorrhoid disease, blood is bright red in colour. Due to mucous secretion or fecal soiling perineal irritation or anal itching is commonly reported in prolapsing hemorrhoids. Pain is reported when thrombosis has occurred particularly in external hemorrhoids.
Treatment Difficulties:
As the rectal tissue and vessels are exposed to variety of germs and toxins in stool, it is difficult to treat Hemorrhoids. Stool contains millions of bacteria and other germs and when it passes through the ruptured mucosal lining of the anal canal these germs get a chance of infection. Due to gram negative and gram positive bacteria present in gut, secondry infections occur and make the condition more worse. A variety of complications can result if not treated properly and on time. Harmful toxins are produced in the body and excreted on daily basis through urine and stool. Metabolic waste products also contain toxins and harmful substances which are excreted through these two major excretory channels. Toxins are present in blood and metabolised by liver, ultimately excreted as fecal material through anal canal. Overly dilated blood vessels in the anal canal in hemorrhoid disease propose a chance for these toxins to leak out and cause destructive changes in normal linings of anal canal. Multiple inflammatory products circulating in blood also may leak out and worsen the condition. Collectively these bacteria, toxins, metabolic waste products and inflammatory mediators make it difficult to treat the hemorrhoids however Proper and effective treatment plan can cure hemorrhoids successfully.
Detox and cleanse treatment:
Detox and cleanse are the natural dietary substances which help human body get rid of toxic substances. Natural organic origin containing detox and cleanse are being used to get rid of chemical toxins and improve health. Use of detox and cleanse for hemorrhoid disease is of great benefit and outstanding results as toxins complicate the treatment process. Once these toxic substances are removed, natural immune system performance is boosted and this leads to improved outcomes and better treatment protocols.
Hemorrhoid detoxification is the fast way to get rid of this condition. Hemorrdetox contains naturally occurring herbs and ingredients that improve mucosal health, clean bacteria and toxins and provide fast relief. Highly selective, low toxicity and cooling effects of herbal origin supplements treat hemorrhoids with much better efficacy and fast results. Moreover all the ingredients are natural and have no side effects as compared to the chemical drugs which contain chemical substances and need detoxification after ingestion.
Sephora flower is a herbal origin medicinal plant used to treat hemorrhoid bleeding. It reduces vasodilation and improves vessel wall health. In hemorrhoids, capillary bed of anal canal is leaky and bleeding occurs. Sephora flowers prevent this bleeding by decreasing blood pressure in capillary bed and help in treatment of hemorrhoids. Hemorrdetox contains this ingredient and helps to prevents hemorrhoid associated bleeding.
Jave Brucea is a detoxifying plant widely used for the treatment of gastrointestinal ailments. Jave Brucea has anti inflammatory activity along with antiviral effects. Its cold character and bitter taste makes it popular in pharmacological applications. Its main effect is to reduce the angioproleferative activity in hemorrhoids hence reducing the size of the lesions. Mucosal hyperplasia is one of the main issue in hemorrhoids, Java Brucea has apoptotic properties which control hyperplasia and treat hemorrhoids. Its acute and chronic anti inflammatory properties decrease the inflammation of anal mucosal linings and help in fast relief from hemorrhoids. With numerous advantages, including a rapid onset of action, convenience, low toxicity, and minimal irritation of the mucosal skin, java brucea is an active component of hemorrdetox.
Lonicera flowers are the naturally occurring organic herbal plants and have antibacterial and germicidal properties. Use of lonicera flowers in hemorrhoids provides antibacterial action which help in treating long standing hemorrhoids. It has cooling effect on body and reduces inflammation. In medicine, lonicera flowers are used for a lot of pharmacological preparations supplemental products. Hemorrdetox contain lonicera flowers and can effectively help to treat hemorrhoids. Lonicera flowers are active detoxifying and cleanse substance which help body get rid of bacteria and toxins causing harm to the anal mucosa.
Cape jasmine has been used for centuries as a traditional oriental herbal remedy. It has hemostatic and laxative properties which help in controlling hemorrhoid associated bleeding and regulate bowl movements. It regulates blood flow and improves blood vessels in hemorrhoid disease. Hemorrdetox contains this herbal supplement and along with other components give quick relief from hemorrhoid disease. Cape jasmine is also beneficial in dysentery and blood in stool.
Redix sacrophulariae preparation has efficacy of clearing heat for detoxification and cooling blood to disperse weakness. It is beneficial in clearing intestines to induce diuresis and aid bowl movements. It diminishes inflammation and helps in subsiding swelling to promote granulation. It activates blood to remove stasis and promotes ulcer healing. Redix sacrophulariae is quick in action, have short treatment period and capable of treating both symptoms and root causes of hemorrhoids. It has remarkable treatment effect on various hemorrhoids like internal hemorrhoids, external hemorrhoids and externo-internal hemorrhoids. Hemorrdetox preparation contains this traditional herbal ingredient which helps to provide quick results to get rid of hemorrhoids.
Scutellaria baicalensis has been widely used as a medicinal plant in China for thousands of years. It has been applied in the treatment of diarrhea, dysentery, hemorrhaging and hemorrhoids.It has multiple pharmacological applications. It has hepatoprotection, antibacterial and antiviral and antioxidant effects which prevent body from harmful toxins and bacteria. It cleanse the gastrointestinal tract and effectively treats hemorrhoids along with other herbal supplements. Hemorrdetox contains scutellaria baicalensis ingredients and help to provide effective treatment against hemorrhoids.
Conclusion:
Hemorrhoids are multifactorial gastrointestinal abnormality in which anal mucosa gets inflamed and toxins and bacteria worsen the condition. Patients complain about perianal itching, bleeding and pain. This condition is because of straining, long standing constipation, chronic diarrhea, heavy weight lifting or excessive body weight as in obesity, pregnancy and anal intercourse. Hemorrhoids are difficult to treat as the toxins in blood and bacterial presence in gastrointestinal tract make the condition worse. To effectively treat the condition, detox and cleanse is necessary. Detox and cleanse can be achieved through effective herbal dietary supplements such as hemorrdetox. Due to rapid onset of action, highly targeting the condition and very low toxicity as compared to other pharmaceutical drugs, hemorrdetox provides quick results with fast relief from hemorrhoids. Both, internal and external hemorrhoids can be effectively managed with hemorrdetox as it is totally natural herbal dietary supplement and proven formula to effectively helps to treat haemorrhoids and promote health.
